As a freshman at Vanderbilt, Disu averaged 7.4 points and 5.7 rebounds per game. On February 17, 2021, he posted career-highs of 29 points and 16 rebounds in an 82–78 loss to
Kentucky. One week later, head coach
Jerry Stackhouse announced that Disu would miss the rest of the season with a knee injury. As a sophomore, Disu averaged 15 points and 9.2 rebounds per game, leading the
Southeastern Conference (SEC) in rebounding prior to his injury. He was named SEC Scholar-Athlete of the Year. After the season, Disu transferred to
Texas, which he described as his "dream school growing up." As a junior, Disu came off the bench and averaged 3.7 points, 3.2 rebounds, 0.4 assists per game in 10.9 minutes a game. As a senior, Disu started in all 36 of the games he played. He averaged 8.8 points, 4.4 rebounds, and 1.0 assist per game in 19 minutes a game. Disu played a crucial part in the Longhorn's post-season, averaging 17.8 points, 9 rebounds, and 1.2 assists per game in the 5 postseason games, consisting of 3 Big 12 Championship games and 2 NCAA Tournament games and excluding the Sweet 16 game against
Xavier where Disu only played 2 minutes due to an injury. Disu won the Big 12 Tournament Most Outstanding Player award and Big 12 All-Tournament Team award. After the end of the 2022-23 season, Disu decided to use his additional year of eligibility granted from
COVID-19 and returned to Texas for his final year. Disu was only able to play in 25 games due to injuries, but left a significant impact on the success of the team as he averaged 15.5 points, 5 rebounds, and 1.5 assists per game. Disu was named as part of the All-Big 12 First-Team and won the Big 12 Most Improved Player award. At the end of the 2023-24 season, Disu declared for the
NBA Draft. ==Professional career==