Edward Thomas MacDonnell was an American college football, college basketball, and college baseball coach. He served as the head football coach at Jefferson College in Convent, Louisiana during the early 1910s, Louisiana State University (LSU) from 1914 to 1916, and Wake Forest University for one season, in 1917. MacDonnell was also the head basketball coach at Wake Forest for the 1917–18 season, tallying a mark of 4–12, and the school's head baseball coach in the spring of 1918, notching a record of 9–3.