Antonio made her debut in round 1, 2017 in the club's inaugural match against at
VU Whitten Oval. She was the first player to be suspended in the AFLW, receiving a one-week suspension for a high bump on Bulldogs defender
Jess Gardner. Antonio returned to play for the Dockers' final five matches of the season. Antonio later played for
The Allies in the inaugural
AFL Women's State of Origin match against
Victoria on 2 September, where she was named among the Allies' best players. Fremantle signed Antonio for the 2018 season during the trade and signing period in May 2017. Antonio had a much improved season in 2018, when she was selected in the
2018 AFL Women's All-Australian team and won the
Fremantle fairest and best award. She had minor surgery on her Achilles following the AFLW season, forcing her to miss most of the WAWFL season with Swan Districts. Fremantle signed Antonio for the 2019 season during the trade and signing period in May 2018. Fremantle signed Antonio for the 2020 season during the trade and sign period in April 2019. Leading into the 2020 season,
womens.afl journalist Sarah Black named Antonio at no. 20 on her list of the top 30 players in the AFLW. She was selected in
womens.afls Team of the Week in round 6, and was selected in the initial 40-woman squad for the
2020 AFL Women's All-Australian team. Leading into the 2021 season, Sarah Black named Antonio at no. 15 on her annual list of the top 30 players in the AFLW. She was named among Fremantle's best players in its record-breaking
Western Derby win over in round 6 with 23 disposals and was selected in
womens.afls Team of the Week for that round. In June 2021, Antonio re-signed with the club for two years. In round 1 of 2022 season 6, Antonio kicked three goals from twelve disposals, including a Goal of the Year contender in the first quarter, in Fremantle's Western Derby win to share the
Western Derby Medal with teammate
Kiara Bowers; she also won the maximum ten coaches' votes and was named in
womens.afls Team of the Week. Antonio was named among Fremantle's best players in its round 4 win over and was best afield in Fremantle's win over the Western Bulldogs a few days later. She was named among Fremantle's best players in its losses to in round 5 and in round 8. Antonio was one of three late outs for Fremantle heading into its record-breaking loss to Melbourne in round 9 due to the AFL's health and safety protocols, before returning in round 10 against . After sitting out the entire
2025 AFL Women's season due to pregnancy, Antonio announced her retirement at Fremantle's Fairest and Best awards night. ==Statistics==