Menarini was founded in 1886 in the small laboratory of the Farmacia Internazionale in
Naples, founded by Doctor Archimede Menarini. Alongside its regular galenic production, the first medicines distributed under the Menarini brand were soon introduced: Metarsile, a solution of digestive ferments with lecithin indicated for the treatment of digestive disorders. In 1972 the headquarters moved from Barcelona to
Badalona, expanding the facilities to 15,000 m². Menarini Spain and its subsidiaries in Central America and the Caribbean focus on research and development of medicines for cardiovascular diseases, anti-inflammatory drugs and pain relief. In 1978, the Menarini Group acquired Malesci, a Florentine pharmaceutical company founded in
1850. In 1982, the first affiliate in
Central America and the
Caribbean was established. The headquarters is located in
Guatemala, where a production plant operates. Lusofarmaco of
Milan and FIRMA. In 1992, the German company
Berlin Chemie (founded in
1890) joined the group, opening up a new market in Central and Eastern Europe. The Research Toxicology Center (RTC) was founded in 1987 in
Pomezia, In 1993, the
L'Aquila plant was inaugurated. In 1994, Menarini entered the Indian market through a partnership with Raunaq Industries and in the same year opened its OTC (over-the-counter medicines) division, followed in 2001 by the acquisition of IE Ulagay, a former Turkish laboratory founded in 1903, and the establishment of its affiliate in
Argentina, with a quality control laboratory in
Buenos Aires. In 2006, the Menarini-von Heyden production plant was inaugurated in
Dresden and in 2008 the Menarini
Mexico affiliate was established. In 2011, Invida was acquired and became Menarini Asia-Pacific, with a presence in numerous South Asian countries. In 2013, the Italian start-up Silicon Biosystems, winner of the 2012 "Premio Leonardo", specialising in rare cell research down to single-cell precision, was acquired and became Menarini Silicon Biosystems. The latter subsequently acquired all corporate activities related to the CellSearch system. In 2014, Menarini Biomarkers was established for the research and development of biomarkers for prenatal diagnosis without amniocentesis, as well as in the field of lung and ocular cancers. In the same year, the group opened a new pharmaceutical production plant in
Kaluga (Russian Federation). In March 2018, the company announced the appointment of a new board of directors, marking the first time that an external manager, Eric Cornut, had taken on the role of chairman. Cornut, a Swiss national from
Basel with a master's degree obtained in
California, spent 20 years at
Novartis and for two years, until April 2017, served as Director General of the EFPIA (European Federation of Pharmaceutical Industries and Associations). On 12 September 2019, the board of directors appointed
Elcin Barker Ergun as chief executive officer of the company. In 2020, Menarini developed a rapid
COVID-19 test amid the
COVID-19 pandemic in Italy, capable of giving a result in just 20 minutes. The same year the group acquired Stemline Therapeutics, a United States-based biopharmaceutical company then listed on the
Nasdaq, specialising in the development of innovative oncology therapies. As of 2025, Menarini Stemline has obtained approval from the main regulatory authorities worldwide for three oncology drugs. == Social causes ==