Because he had an interest in art, Wuerpel entered the
Washington University School of Fine Arts upon his return to St. Louis in 1887. In order to further his training, he left for Paris, which was then the most popular training grounds for American art students. He studied at the private
Académie Julian and the
Ecole des Beaux Arts, the official state sponsored art school, where the tuition was free if you passed the "concours" for admission. Wuerpel studied with Jean Aman-Jean,
Jean-Léon Gérôme and
Tony Robert-Fleury. In Paris he became close friends with James Abbott McNeill Whistler, the expatriate American painter and eccentric raconteur. Whistler wrote to his sister Beatrice of him: "As I told you this morning Wink, poor Mortimer seems to have had rather a cold time of it with this spoil he meandered back from Wuerpel's country with! - don't you think so? Dear me! when are we going to write to the good kind Wuerpel! - Well when I am sitting by you in a day or two! we will get off a whole batch of letters! wont we Chinkie" In old age he recalled that Whistler had requested that his painting "Nocturne: The Solent" hang next to Wuerpel's at the Paris Salon. Wuerpel had a reputation for being an interesting man and he also became acquainted with
Rodman Wanamaker,
Sarah Bernhardt and
Whitelaw Reid. John Wanamaker, Rodman's father and the founder of the famous Philadelphia store of that name was one of his first clients and he purchased a painting in 1894, the year that Wuerpel returned home. and soon began teaching at the Washington University School of Fine Arts. He initially taught the life class. The American Impressionist
Richard E. Miller was one of his first students and began painting in a tonal style while working under Wuerpel. Another of his early students was an American woman
Wilhelmina Weber Furlong shortly after her arrival in Paris in the late 1890s she abandoned Wuerpel's style of tonalism. Wuerpel succeeded Ives as director of the School of Fine Arts and went on to teach for 58 years, the longest career of any member of the staff at Washington University. Wurpel remained director for more than thirty years and taught more than 10,000 young art students. ==Personal life==