Kayembe signed his first professional contract on 22 November 2016 with
R.S.C. Anderlecht for 4.5 years, joining from the Congolese club
Sharks XI FC. He made his professional debut for Anderlecht in a 1–0
Belgian First Division A win over
K.A.S. Eupen on 22 December 2017. On 7 January 2022, Kayembe joined
Premier League club
Watford on an eight and-a-half-year contract. Kayembe scored his first goal for Watford FC on 11 November 2023 during a league match against
Rotherham United FC. As a starter, he contributed to his team's 5–0 victory. ==International career==