The Eisner Award for Best Graphic Memoir is an American comic book award presented annually to recognise creative achievement in graphic memoirs, a form of non-fiction and autobiographical comics. The category was established in 2021 after being separated from the Best Reality-Based Work award, reflecting the growing prominence of graphic memoirs within the medium. It honours works that combine personal or factual narratives with the visual storytelling of comics and is presented as part of the Eisner Awards at San Diego Comic-Con.