Matthews was an alumna of
St Hilda's College, Oxford, where she took a BA in
Literae Humaniores (1960–64) and was a pupil of
Barbara Levick. She went on to take the
MPhil (then
BPhil) in Ancient History, working on
Lucian. After a break to raise her two daughters, Matthews embarked on a research career in Greek
onomastics at the
University of Oxford. In 2010, after she had retired, she was the dedicatee of a
Festschrift on
Ancient Greek personal names in honour of her distinguished career, containing a collection of scholarly essays on Greek onomastics but with an appreciation of Matthews as a scholar by
Alan Bowman as its first chapter. She was a supernumerary fellow of
St Hilda's College, Oxford, from 1996 and was honorary secretary for the
Society for the Promotion of Roman Studies, of which she was also a trustee, for twenty-one years. ==Personal life==