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Rufus Sewell as Dr. Jacob Hood – a science adviser to the FBI, called in to investigate crimes that may have a scientific explanation. Even though Hood is extremely brilliant, he sometimes gets lost in his own thoughts, and this, coupled with his low attention span and poor social skills, causes him to be viewed as odd. He also has few instincts of self-preservation or danger, causing him to often do things that put his life in jeopardy, such as standing in front of a fleeing suspect's car to get the license plate, something that frequently annoys Rachel. Additionally, he does not know how to drive well, leading Rachel to insist she do all the driving. Hood appears to be an atheist and is knowledgeable on a number of scientific, mathematical and philosophical topics. He nursed his wife, who died of cancer, throughout her illness. •
Marley Shelton as FBI Special Agent Rachel Young – Hood's handler. Though she is employed to protect his life, she has also said that her job is "to protect him from himself" – something he makes very difficult for her. Hood might annoy her from time to time but she does care about his well-being, viewing his many techniques with a kind of exasperated affection, though she is frequently embarrassed by and for him. Rachel mainly gets annoyed when he gets too caught up in an investigation and does something stupid, or when he does things like accidentally sit on his panic button. It is noted throughout the series that Dr. Hood is her only friend, though male characters frequently flirt with her. She is the latest in a line of Hood's protectors, but she refuses to let him "drive her away like he did those others." •
Omar Benson Miller as FBI Special Agent Felix Lee (episodes 14–18) – introduced later in the series when he asks (although it is later discovered that he begged) to help Jacob Hood on a case. After solving the case, he asks to work with Hood full-time, stating that the work they do is amazing. Felix is given the job and works as somewhat of a scout, helping out the team with heading to the location and gathering the material they need by the time Hood and Young get there. Though he likes the job, Felix feels underappreciated due to the lack of praise for the amount of work he does. ==Production==