2021: First ITF Circuit title She won her first W60 title at the
Reinert Open as a lucky loser.
2022: WTA Tour, major and WTA 1000 debuts She made her
WTA Tour debut at the
2022 Copa Colsanitas, where she reached the quarterfinals, and her major debut as a qualifier at the
US Open. She also made her debut at the WTA 1000 level at the
Italian Open as a qualifier, and also entered the main draw of the new WTA 1000
Guadalajara Open as a lucky loser.
2023: French Open fourth round, top 65 Ranked No. 134, Avanesyan made her debut at the
French Open as a lucky loser. In the first round, she upset 12th seed
Belinda Bencic for her first major and top-20 win. She defeated French wildcard
Léolia Jeanjean in the second round and qualifier
Clara Tauson in the third, becoming the first lucky loser at Roland Garros in the last 16 in 35 years since 1988 and only the fifth overall at this major. As a result, she reached the top 80 rising 54 positions in the rankings on 12 June 2023. She made her WTA 500 debut at the
German Open, also as a lucky loser and defeated eighth seed
Daria Kasatkina. As a result, she reached a new career-high ranking of No. 64, on 26 June 2023. She reached the second round of the
US Open by defeating
Alizé Cornet in the first round. At the same tournament, she reached the third round in doubles, partnering
Kamilla Rakhimova as an alternate pair, defeating 10th seeded pair of
Jelena Ostapenko and
Lyudmyla Kichenok, but lost to eight seeds
Hsieh Su-wei and
Wang Xinyu. She finished the year ranked No. 75.
2024: Australian Open debut, first top 10 win & WTA Tour final, top 50 On her debut at the
Australian Open, she recorded two wins over
Bai Zhuoxuan and eighth seed
Maria Sakkari, her first top 10 win. On her debut at
Indian Wells, she lost to
Océane Dodin. On another debut at the
Miami Open, she recorded her first WTA 1000-level win over wildcard
Erika Andreeva, and her second top 10 and biggest win of her career, over sixth seed
Ons Jabeur, to reach her first third round at this level. At the
French Open, she reached a consecutive fourth round with wins over
Zhu Lin,
Anna Blinkova and seventh seed
Zheng Qinwen. Her run was ended by 12th seed
Jasmine Paolini. At
Wimbledon, she reached the second round for the first time with a win over
Anhelina Kalinina in her opening match. She lost in round two against 15th seed
Liudmila Samsonova. Avanesyan made it through to the quarterfinals at the
Budapest Grand Prix, defeating fifth seed
Magdalena Fręch and
Rebeka Masarova before losing to
Anna Karolína Schmiedlová in three sets. Avanesyan reached her first WTA Tour semifinal at the
Iași Open, defeating third seed
Jaqueline Cristian in the quarterfinals. In the last four, Avanesyan defeated
Chloé Paquet and advanced into her maiden WTA Tour final which she lost to
Mirra Andreeva when she retired injured while trailing in the third set. She recorded her first tour main-draw win under her new Armenian nationality at the
Cincinnati Open as a lucky loser, making history for her country as the first player to do so, over wildcard
Bianca Andreescu. Next, she defeated eighth seed
Jeļena Ostapenko to reach her second WTA 1000 third round, where she lost to tenth seed Liudmila Samsonova. At the
Wuhan Open, she lost a three-setter to 13th seed
Marta Kostyuk in the first round. Seeded fifth at the
Japan Women's Open, Avanesyan defeated defending champion
Ashlyn Krueger, before going out to local wildcard
Sara Saito. She finished the year ranked inside the top 50.
2025: First Armenian in WTA 500 semifinal Avanesyan started her 2025 season at the
Brisbane International, defeating
Rebecca Šramková and fourth seed
Paula Badosa, before losing to
Ons Jabeur in the third round. The following week, at the
Hobart International, she overcame qualifiers
Wang Xiyu and
Greet Minnen, then benefitted from the withdrawal of third seed
Amanda Anisimova to reach the semifinals, where she lost to eventual champion
McCartney Kessler. At the
Mérida Open in Mexico, Avanesyan became the first Armenian player to reach a WTA 500 semifinal with a win over
Maya Joint. She lost in the last four to top seed and eventual champion
Emma Navarro. ==Performance timeline==