Tupper taught school in
Mount Pleasant, Iowa as a young woman, hoping that her training as a teacher would prepare her for life as a Baptist missionary. However, she converted to Universalist instead, and became a minister in that denomination, preaching first in Iowa, then Wisconsin, then Minnesota, where she was ordained in 1871. After her husband became a lawyer, the family moved to Colorado, where she organized a new church in Colorado Springs. In 1875 she attended the first Women's Ministerial Conference, hosted in Boston by
Julia Ward Howe. In 1876 she was one of the founding leaders of
Colorado College. Once the churches were established, she handed them to another pastor, often another woman pastor from the
Iowa Sisterhood. She was director of the Iowa Unitarian Conference. and was president of the Western Woman's Unitarian Conference. Late in life, she was chaplain of the
Cumnock School of Expression in Los Angeles. == Suffrage ==