In 1952, at the age of 77, Patterson made her first appearance on the hit CBS-TV
sitcom I Love Lucy in the episode "The Marriage License". In that installment, Patterson's character, Mrs. Willoughby, is married to the
Greenwich, Connecticut,
justice of the peace (played by character actor
Irving Bacon) who remarries Lucy and Ricky Ricardo. In that role, she most notably sings an off-key version of "
I Love You Truly" during the wedding ceremony. The following year she was cast in a featured guest role as Mrs. Matilda Trumbull in the episode "No Children Allowed". Patterson's character of Mrs. Trumbull was initially an ornery curmudgeon who resided in the same New York apartment building as the Ricardos. In that installment, she threatened to make trouble for the Ricardos since the building did not allow children. At the end of the episode, however, her character softens as she holds for the first time the Ricardos' baby, "Little Ricky"; and, as a result, Mrs. Trumbull becomes friends with both the Ricardos and the building's owners, Fred and Ethel Mertz. Patterson's character on
I Love Lucy proved to be so popular among viewers, as well as useful to the writers of the series, that she continued in the role for three more years, often serving in episode storylines as a convenient babysitter for "Little Ricky". In the fall of 1956, with
I Love Lucy in its final season, Patterson made her last appearance as Mrs. Trumbull in "Little Ricky Learns to Play the Drums". Her character was mentioned one last time in the 1957 episode "Lucy Raises Chickens". In that installment, Fred and Ethel decide to follow the Ricardos and move to Connecticut to be near them, and Mrs. Trumbull's sister moves into 623 East 68th Street to manage the apartment building for the Mertzes. ==Personal life and death==