Enza-Yamissi started his playing career at
Bordeaux. He was there one season and did not make a first team appearance. He then signed for
La Roche VF, spending one season there, playing six games. He then moved to
Olympique Alès, where he played only four games, before moving to
Nîmes Olympique, where his career began to take off, playing 52 games and scoring four goals. His potential was noticed by
Troyes AC, which promptly signed him in 2005, when it was in
Ligue 1. He experienced several ups and downs at the club, being relegated twice, and winning promotion twice too. From 2011, he was club captain, which he led to promotion to Ligue 1 once again at the end of the 2011–12 season. He joined
Valenciennes FC in 2013 and played five seasons for the club before being released in 2018. In February 2019 he joined
Annecy FC. On 28 May 2020, it was announced that his contract at Annecy, which had just been promoted to the
Championnat National, would not be renewed. In summer 2022, after two seasons at
Racing Besançon, Yamissi retired from playing and became assistant coach to
David Le Frapper at the club.
Central African Football Federation appointed Enza-Yamissi as a caretaker manager of Central African Republic national team on 24 October 2024, replacing
Raoul Savoy. ==International career==