After returning home for several years of teaching and coaching, he decided to attend medical school at
Indiana University, from which he received a degree in medicine in 1928. In 1930, after struggling to maintain a general practice during economically difficult times, he took a faculty post at the
University of Wisconsin–Madison, where he studied under Dr.
Ralph M. Waters and served as assistant professor of anesthesia. He and Waters experimented on the gas cyclopropane and were the first doctors to use it on human subjects. In 1935, Rovenstine was appointed chair of the department of anesthesiology at
Bellevue Hospital, where he was influential in shaping the department's mission and mentoring future generations of anesthesiologists. During this time he developed a nerve blocking technique and became the first anesthesiologist to set up a nerve blocking clinic for pain relief. Two years later, he was appointed the second American professor of anesthesiology at
New York University School of Medicine. He became director at
Goldwater Memorial Hospital in 1938 and director at University Hospital a decade later. Also in 1938, he accepted a guest professorship at
Oxford University in England, and, a year later, at
University of Rosario in Argentina. He also accepted visiting appointments in Bohemia, Canada, Cuba, Czechoslovakia, France, Japan, Mexico and South Africa – and was inducted into the medical society of each respective nation. During
World War II, Rovenstine served on the Army Advisory Board and was responsible for an order to Army general hospitals placing operating rooms in charge of anesthesiologists. The practice later became general. Rovenstine was a co-founder of the reorganized
American Society of Anesthesiologists and served as its president from 1943 to 1944. In 1957, he received that Society's Distinguished Service Award. He was also the founder of the PostGraduate Assembly (PGA) in Anesthesiology and the
American Board of Anesthesiology. He was honored by numerous organizations and governments, notably being decorated at the Verdun by the French government (for his service in the war), and being decorated by the
Order of the White Lion in Czechoslovakia (for a humanitarian teaching mission there). == Residents ==