Archaeological evidence shows Celtic and Roman traces in the area. The site of a Roman temple was of special interest. In medieval times there were two Lordships (
heerlijkheid) in the area. The Lordship of Empel and the Lordship of Meerwijk, but as they were always in one hand, they became known as Lordship of Empel en Meerwijk. The center was in the village now called Oud-Empel.
Empel en Meerwijk Castle, the seat of the Lord of Empel en Meerwijk, was in an area called 'Het Slot', Dutch for 'The Castle'. When Empel village was moved later on, it came to lie inside the new Empel village. During the
Eighty Years' War the area suffered greatly, because it was on the frontline from 1579 till 1609, and then again from 1621 to 1629. Empel village was even abandoned for some decades, and the Castle was probably also ruined in these years. In 1585 the
Battle of Empel was named for the village now called Oud-Empel. In the eighteenth century the owner of the castle built a new manor
Meerwijk Castle at Dieskant on the
Dieze, hastening the decay of the medieval castle. During the
French period the lordships were abolished, and the new municipality of Empel en Meerwijk was formed, with Empel village on the Meuse as seat of the municipal government. In the closing phases of
World War II Empel village on the Meuse dyke was heavily damaged. Its Catholic church was subsequently demolished. From about 1949 the village with church was rebuilt as an
Angerdorf at the current location. This was southeast of the old village, which was then renamed Oud-Empel. A new townhouse was also built on the new location of Empel. In 1971 the entire municipality of Empel en Meerwijk was absorbed by 's-Hertogenbosch municipality. Empel then grew to a city quarter of 6,505 inhabitants. As a city quarter Empel includes the
neighbourhoods: Maasakker, De Koornwaard, Empel-Oost and Empel-Zuid. Oud-Empel became part of Maaspoort. ==Points of interest==