Nutrition Nutrition has been shown to affect intelligence
prenatally and
postnatally. The idea that prenatal nutrition may affect intelligence comes from
Barker's hypothesis of fetal programming, which states that during critical stages of development the intrauterine environment affects or 'programmes' how the child will develop. Barker cited nutrition as being one of the most important intrauterine influences affecting development and that under-nutrition could permanently change the
physiology and development of the child. It has been shown that under-nutrition, particularly protein malnutrition, can lead to irregular brain maturation and
learning disabilities. As prenatal nutrition is difficult to measure, birth weight has been used as a surrogate marker of nutrition in many studies. Birth weight needs to be corrected for gestational length to ensure that the effects are due to nutrition and not prematurity. The first longitudinal study looking at the effects of under-nutrition, as measured by birth weight, and intelligence focused on males who were born during the Dutch famine. Another study done by Lucas et al. confirms the conclusions about the importance of nutrition in the cognitive development of individuals born prematurely. It also found that the
cognitive function of males was significantly more impaired by poorer postnatal nutrition.
Breast feeding has long been purported to supply important nutrients to infants and has been correlated with increased cognitive gains later in childhood. The link between intelligence and breast feeding has even been shown to persist into adulthood. However, this view has been challenged in recent times by studies which have found no such link between breast feeding and cognitive abilities. A meta-analysis by Der, Batty and Deary concluded that there was no link between IQ and breastfeeding when maternal intelligence had been accounted for and that mothers' intelligence is likely to be the link between breastfeeding and intelligence. Other studies have indicated that breast feeding may be particularly important for children born
Small for Gestational Age (SGA). A study by Slykerman et al. found that there was no association between breast feeding and higher intelligence in their full sample but that when looking only at SGA babies there was a significant increase in intelligence for those who had been breastfed over those who had not. A 2007 study provides a possible resolution to the different results found across studies investigating breastfeeding's effect on intelligence. Caspi
et al. found that whether breast feeding increased IQ was linked to whether the infant had a certain variant of the FADS2 gene. Children with the C variant of the gene showed an IQ advantage of 7 points when breastfed, whereas those with the GG variant showed no IQ advantages with breastfeeding. However, other studies have failed to replicate this result. Certain single-gene
metabolic disorders can severely affect intelligence.
Phenylketonuria is an example, with publications documenting the capacity of treated phenylketonuria to produce a reduction of 10 IQ points on average. Meta-analyses have found that environmental factors, such as
iodine deficiency, can result in large reductions in average IQ; iodine deficiency has been shown to produce a reduction of 12.5 IQ points on average.
Sleep The effects of sleep deprivation on intelligence performance have been studied.
Stress Maternal stress levels may affect the developing child's intelligence. The timing and duration of stress can greatly alter the fetus' brain development which can have long-term effects on intelligence. Maternal reactions to stress such as increased heart rate are dampened during pregnancy in order to protect the fetus. The impact of stress can be seen across many different species and can be an indicator of the outside environment which can help the fetus to adapt for surviving in the outside world. However, not all maternal stress has been perceived as bad as some has been seen to induce advantageous adaptions. Stress during early childhood may also affect the child's development and have negative consequences on neural systems underlying fluid intelligence. A 2006 study found that IQ scores were related to the number of traumas and symptoms of
post traumatic stress disorder (PTSD) in children and adults. Similarly, another study found that exposure to violence in the community and the subsequent distress, were related to a significant decrease in intelligence scores and reading abilities in children aged 6–7 years. Exposure to violence in the community had similar cognitive effects as experiencing childhood maltreatment or trauma.
Maternal age Maternal age has been shown to be related to intelligence with younger mothers tending have children of lower intelligence than older mothers. However, this relationship may be non-linear with older mothers being at increased risk of giving birth to children with down syndrome which greatly affects cognitive abilities.
Exposure to toxic chemicals and other substances Lead exposure has been proven to have significant effects on the intellectual development of a child. It is estimated that 1 in 1,000 babies born in the general population are born with fetal alcohol syndrome, as a result of heavy use of alcohol during pregnancy. However, studies have shown that even at slightly less severe doses, prenatal exposure to alcohol can still affect the intelligence of the child in development, without having the full syndrome. Through a study done by Streissguth, Barr, Sampson, Darby, and Martin in 1989, it was shown that moderate prenatal doses of alcohol, defined as the mother ingesting 1.5 oz. daily, lowered children's test scores by 4 point below control levels, by the age of four. They also showed that prenatal exposure to
aspirin and
antibiotics is correlated with lower performance on intelligence tests as well. This contradictory evidence could perhaps be explained by findings that the effects of alcohol may depend on the genetic makeup of the fetus. In a recent study Lewis et al., looked at alcohol dehydrogenase genes and their mutations, which humans can have between 0 and 10. These mutations slow the breakdown of alcohol so the more mutations the fetus has the slower they will breakdown alcohol. They found that in children whose mothers had drunk moderately, those children with four or more mutations performed worse on an intelligence test than those with two or less mutations. In another study, prenatal drug exposure was shown to have significantly negative effects on cognitive functioning, as measured at the age of five, compared again controls matched for socioeconomic status and inner-city environment. The researchers concluded that prenatally drug-exposed children are at greater risk for
learning difficulties and attention problems in school, and therefore should be the subject of interventions to support educational success. It could be hypothesized that the effect of these drugs on the development of the brain prenatally, and
axon guidance could be the root of the negative consequences on later deficits in intellectual development. Specifically,
prenatal exposure to marijuana affects development of intelligence later in childhood, in a nonlinear fashion, with the degree of exposure. A study by Fried and Smith indicated that marijuana exposure did not lead to a decrease in global intelligence but that it did lead to problems with executive functions in childhood. However, another study found that when influences such as maternal age, mother's personality and home environment, there was no longer a difference between children exposed to marijuana and those not exposed with relation to executive functions. Exposure to tobacco smoking has been associated with diminished intelligence and attentional problems. One study indicated that children whose mothers had smoked 10 or more cigarettes a day were between 3 and 5 months behind schoolmates in reading, maths and general ability. However, other studies have found no direct link between IQ and tobacco smoking with maternal intelligence accounting entirely for the relationship.
Perinatal factors There is also evidence that birth complications and other factors around the time of birth (perinatal) can have serious implications on intellectual development. Other studies have also found that the correlations are relatively small unless the weight is extremely low (less than 1,500 g) – in which case the effects on intellectual development are more severe and often result in intellectual disability. == Genetic influences ==