Eperythrozoon

The members of this genus have variously been named under Eperythrozoon, Haemobartonella (before that, Bartonella), and Mycoplasma. When they were under Mycoplasma, most species had a specific epithet starting with hemo or haemo (meaning "blood"), giving them the informal name "hemoplasmas" or "hemotrophic mycoplasmas". The merge into Mycoplasma is now known to be misguided and resulted in a polyphyletic Mycoplasma. The current circumscription of the genus is by Gupta et al. (2018). This article nevertheless uses these names because they imply a monophyletic Mycoplasma. For more background on resistance to renaming medically-important bacteria, see . Species include: • "E. canis" • E. coccoides – type species • "Candidatus E. haematobovis" • "Candidatus E. haematolamae" • "Candidatus E. haematominutum" • "Candidatus E. haemobos" • "Candidatus E. haemolamae" • "Candidatus E. haemominutum" • "E. muris" • E. ovis • E. parvum S • E. suis • E. wenyonii Additional possible members can be found in . Several hemotrophic species published after 2018 were named under Mycoplasma despite the 2018 change. == Clinical relevance ==

Eperythrozoon infection can cause fever, hemolytic anemia, and jaundice in infected animals (domestic, wild, and humans). Humans Eperythrozoon ovis and Eperythrozoon parvum have been implicated in human infections. It is believed to spread by contact with animals or arthropods, but cases have been reported without extensive contact. Diagnosis is by blood smear microscopy or PCR. Definite identification of the species responsible can be achieved through gene sequencing. "Ca. Mycoplasma haemohominis", as the name suggests, is originally found in a human. A case report describes identification of the bacterium and its quinolone antibiotic resistance mutation through genome sequencing. The patient was treated successfully with moxifloxacin and minocycline combination. == Phylogeny ==

For now, consult Gupta et al. (2018). Trees extracted from 'The All-Species Living Tree' Project (16S ribosomal RNA) and GTDB (120 marker genes) will be included in the article at a later date. == References ==