Mabius began his career with roles in
Welcome to the Dollhouse (1995),
I Shot Andy Warhol (1996), and
Black Circle Boys (1997). He was involved with
The Crow superhero franchise on more than one occasion: he auditioned for a role as one of Top Dollar's henchmen in the 1994 original
The Crow and played
Alex Corvis in
The Crow: Salvation (2000), the third installment, opposite
Kirsten Dunst. He was in
Cruel Intentions (1999) alongside
Sarah Michelle Gellar and
Ryan Phillippe. He also played an activist named
Matt Addison in 2002's
Resident Evil. In television, Mabius has appeared on
Chicago Hope,
Millennium,
Popular,
The O.C., and the short-lived series
Eyes (2005). He was a regular cast member of
The L Word in its first season and returned for one episode in each of the second, third, and sixth seasons, portraying
Tim Haspel. He also guest-starred on an episode of
CSI: Miami. From 2006 to 2010, he starred as fashion magazine editor
Daniel Meade on the
ABC dramedy series
Ugly Betty. After the success of
Ugly Betty, he was included on
People magazine's "Sexiest Men Alive" list in 2006. Mabius also appeared in the 2006
Lifetime original film
A Christmas Wedding, and had a leading role in the 2011 British science-fiction drama series
Outcasts. In 2013, Mabius guest-starred in a season 2 episode of
Scandal. The same year he was cast as the lead in
Hallmark Channel's
Signed, Sealed, Delivered film series. ==Honors==