Murillo is a Spanish surname. Notable people with the name include:Ander Murillo, Spanish footballer Bartolomé Esteban Murillo (1617–1682), Spanish artist Catalina Murillo Valverde, Costa Rican writer Jeison Murillo, Colombian footballer Jesús Murillo Karam, governor of Hidalgo and attorney-general of Mexico Juan Murillo, Venezuelan road cyclist Manuel Murillo Toro (1816–1880), Colombian president and writer Marino Murillo, Cuban communist official Mario Murillo (footballer) (1927–2012), Costa Rican footballer Mario A. Murillo, American journalist, public radio personality, author, and academic Óscar Murillo, Colombian footballer Oscar Murillo (artist), Colombian artist Pedro Domingo Murillo (1757–1810), independentist leader of Bolivia Pedro Murillo Velarde (1696–1753), Spanish Jesuit and cartographer of the Philippines Soledad Murillo, Spanish academic and politician