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ESAT-6

ESAT-6 or early secreted antigenic target 6 kDa, is produced by Mycobacterium tuberculosis, it is a secretory protein and potent T cell antigen. It is used in tuberculosis diagnosis by the whole blood interferon γ test QuantiFERON-TB Gold, in conjunction with CFP-10.

ESAT-6 and CFP-10
There are also connections between the ESAT-6 marker and the CFP-10 marker. These are both produced in Mycobacterium tuberculosis cells and are subject to a positive correlation of virulence to the amount of protein produced. Recent work shows that the production of these proteins is a process that is caused by the flanking genes. ==References==
Source: Wikipedia ↗
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