Escadrille Spa.561 was a French First World War fighter squadron dedicated to defending Venice, Italy, from aerial attack. Stemming from a six plane detachment assigned to Venice's defense on 15 August 1915, after its foundation in June 1916, Escadrille Spa. 561 would defend Venice until 1 January 1918. Detached then to support the French X Armee during its sojourn in Italy, the squadron remained on the peninsula after the X Armee had returned to France. By war's end, Escadrille Spa.561 was credited with destroying 12 enemy aircraft and four observation balloons.