Esco may refer to the following people:Given nameEsco Sarkkinen (1918–1998), American football player and coach Esco Haynes, American professional baseball player Esco Niblo Bowen, American lawyer, judge and politician Sigmund Esco Jackson, American singer and musician William Esco Moerner, American physical chemist and chemical physicist awarded Nobel Prize in Chemistry in 2014SurnameLina Esco, American actressNicknameDJ Esco, American DJ from Georgia Nas, nicknamed Esco, American rapper