A lightweight bout between former
UFC Lightweight Champion Rafael dos Anjos and
Rafael Fiziev headlined the event. They were previously scheduled to headline
UFC Fight Night: Walker vs. Hill, but the bout was postponed to
UFC 272 due to visa issues with Fiziev. Fiziev was once again forced to withdraw as he
tested positive for COVID-19 a week before that event. A women's flyweight bout between
Antonina Shevchenko and
Cortney Casey took place at this event. The pairing was previously scheduled to meet at
UFC on ESPN: Font vs. Vera, but the bout was postponed to this event due to Shevchenko injuring her knee in training. A middleweight bout between Josh Fremd and Tresean Gore was scheduled for the event. However, Fremd was pulled from the fight due to injury and replaced by
Cody Brundage. Former
UFC Bantamweight Champion Cody Garbrandt and
Rani Yahya were expected to meet in a bantamweight bout. However, Yahya withdrew in mid June due to a neck injury and the bout was scrapped. A middleweight bout between
Jamie Pickett and
Abdul Razak Alhassan was scheduled for this event. However, Alhassan pulled out of the bout and was replaced by Denis Tiuliulin. The bout was removed from the card for undisclosed reasons and moved to
UFC 279.
Sijara Eubanks was scheduled to face
Maryna Moroz in a women's flyweight bout at this event. However, the pair was moved to
UFC Fight Night 210 due to undisclosed reasons. A featherweight bout between
Austin Lingo and David Onama was scheduled for the event. Lingo pulled out during fight week and was replaced by promotional newcomer Garrett Armfield. A women's flyweight bout between
Cynthia Calvillo and
Nina Nunes was expected to take place at the event. However, the day of the event, Nunes withdrew due to illness and the bout was canceled.
Charly Arnolt debuted as an interviewer at the event. ==Results==