Esther Lipsen was born on January 18, 1930, in
Des Moines, Iowa; her father was an emigrant cattle dealer from present-day
Moldova and her mother was a homemaker from
Romania. She became actively involved in politics in 1952, when she filled in to chair an event for the presidential
Democratic hopeful, Tennessee senator
Estes Kefauver, who went on to win the Wisconsin
primary election and 11 of the 15 others across the country, even defeating sitting President
Harry S. Truman, who then withdrew his re-election campaign. Kefauver asked Lipsen to open and manage a campaign office for the Chicago convention. Not having any experience with such a job, she asked a rival politician's aides for advice. Despite Kefauver's popularity and campaign success, he lost the Democratic nomination to Illinois governor
Adlai Stevenson II. Lipsen then organized Young Democrat campaign clubs to support Stevenson. Although Kefauver invited her to Washington, D.C., in 1954, he did not hire her, despite his desire to run in future presidential elections. ==Wife, diplomat, and ambassador==