Valdez became part of the series
Marinella starring
Camille Prats,
Shaina Magdayao and
Serena Dalrymple but she gained more popularity during her portrayal as "Amor de Jesus-Powers" in the
ABS-CBN television series
Pangako Sa ’Yo in 2000 starring
Kristine Hermosa,
Jericho Rosales and
Jean Garcia. In 2003, she was cast as Mira B. Cordero in the drama series
Darating ang Umaga created by
Jose Javier Reyes, but the series garnered low ratings. In 2005 she joined ''
Pablo S. Gomez's Kampanerang Kuba'' playing Lourdes Saavedra. In 2007 she starred in the TV series
Maria Flordeluna, and after the ending of the series she did a follow-up series on ABS-CBN's rival network titled
Kamandag aired on
GMA Network starring
Richard Gutierrez. Since then she became part of GMA Network's female lead actress and starred in multiple series such
All About Eve, the short-lived Saturday paranormal series
E.S.P. and
LaLola. In 2009, she went back to ABS-CBN to do the primetime hit series
The Wedding, then in 2010
The Last Prince and the afternoon series
Koreana. In 2011, Eula was part of the remake of
Mula sa Puso as her comeback project to ABS-CBN where she played Selina Matias (originally portrayed by
Princess Punzalan based on the
1997 primetime drama series of the same name). On the 20th anniversary of
MMK, she is the most featured actress with the most episodes (32 episodes, as of 2014) and she was hailed "MMK Queen". In 2012, as her comeback as a contract artist she plays Olivia La Peña-San Juan on the film remake turned TV series
Mundo Man ay Magunaw which was originally portrayed by
Susan Roces and will be Black Lily at the book two of
Walang Hanggan. In 2014, Valdez returned to GMA-7 after
Dyesebel and did
Ilustrado,
Elemento,
The Half Sisters, two
TAPE Inc. - GMA Network produced shows,
Princess in the Palace and
Calle Siete,
Hahamakin ang Lahat, and the reboot role of Queen Avria in the 2016 version of
Encantadia. In 2017, she switched back to ABS-CBN. She starred in the TV series
The Good Son wherein she portrayed the role of Olivia Buenavidez, the manipulative and scheming wife of Victor Buenavidez. In 2019, she starred in ''
The General's Daughter, portraying Corazon de Leon, a loving wife and mother. Then in 2020, she played Lucy Wong in Love Thy Woman, a fierce and overprotective mother and wife. In 2021, she portrayed Deborah delos Santos in Huwag Kang Mangamba'', a religious fanatic turned faith healer. In 2022, she returned to
GMA Network as Amanda in
Return to Paradise. ==Awards==