Picardo was a co-founder of the Gibraltar National Party in 1991, the predecessor to the
Liberal Party of Gibraltar. In 2003, he joined the
Gibraltar Socialist Labour Party (GSLP) and was elected as a member of parliament (MP) for the GSLP in that year's
general election.
David Lidington in London on 2 December 2015. Picardo has described what made him interested in politics as a lawyer in Gibraltar: "I started to wake up to politics and see what Hassan had done, and I started to understand what Joe Bossano was doing. I realised that if I had the ability to become a lawyer then I should use that ability also in the interests of Gibraltar. Gibraltar is a place where all of us have to pull our weight; we all have to do what we can and I wanted to do what I could in politics." Picardo became the leader of the Gibraltar Socialist Labour Party in 2011, taking over from
Joe Bossano. He won the 2011 election, forming a coalition government with the Liberal Party. In October 2015, he said that if
Brexit took place, Gibraltar "would have to carefully reconsider what the economic prospects for Gibraltar are and how we would be positioned." During the election campaign, Picardo stated that the 2023 election would be his last, and he planned to step down as Chief Minister of Gibraltar and Leader of the Gibraltar Socialist Labour Party at some point during the 14th Parliament of Gibraltar. He also took the opportunity to suggest he would be in favour of Health Minister Gemma Arias Vasquez replacing him in both positions but noted that the party would ultimately select who succeeded him. However, on 5 November 2024, he announced he would remain as Party Leader for the next general election, subject to an uncontested AGM the week after. == McGrail Inquiry ==