Born in
Treia, Melchiorri started his career with
Serie D amateurs
Tolentino and successively joined
Siena in January 2006. He made his
Serie A debut on 20 December 2006 in a game against
Empoli when he came on as a last-minute substitute for
Cristian Molinaro. Melchiorri was sold to
Sambenedettese in
co-ownership deal in 2007. He was then fully signed by Sambenedettese in 2009. He was successively forced to quit football after being diagnosed with
cavernoma and undergoing surgery as a result. He resumed active football later in 2010 with former club Tolentino (
Eccellenza), scoring 30 goals in 54 matches. In 2012–13 Melchiorri was sold to
Maceratese (
Serie D) and he scored 22 goals in 30 matches. His impressive performances caught the attention of
Serie B club
Padova, who signed him in the summer of 2013. He scored six goals in a rather unfortunate season for Padova, which ended with relegation and then the club being declared bankrupt. He successively joined
Pescara, another Serie B club, in the summer of 2014 on a free transfer. On 8 January 2018, he was loaned to
Carpi. On 12 July 2018, Melchiorri signed with
Perugia. On 31 August 2021, he moved on loan to
SPAL. On 27 January 2023, Melchiorri signed with
Ancona until 30 June 2023. ==References==