In 1790, after
his fort was chosen as the capital for the newly created
Southwest Territory, James White asked his son-in-law, surveyor Charles McClung, to lay out a new town, named "Knoxville" after Secretary of War
Henry Knox. McClung initially divided the town into 64 half-acre (0.2-ha) lots, and added additional lots in 1795, with the cemetery lot being included in the later additions. During the
Civil War,
Confederate soldiers (who occupied the town 1861–1863) kept horses in the cemetery, and
Union soldiers (who occupied the town 1863–1865) used the church as a hospital and barracks. Humorist
George Washington Harris (1814–1869), an ardent Presbyterian, served as an elder of the First Presbyterian Church during his years in Knoxville. Two of his children, Harriet (1838–1846) and George (1841–1842), are buried in the graveyard. In the 1870s, the graveyard had an indirect effect on the career of future newspaper publisher,
Adolph Ochs. Ochs, then a young teenager working after hours as a "printer's devil" for the
Knoxville Chronicle, feared walking past the graveyard at night, as many locals believed it to be haunted. Rather than leave work after his shift (which ended close to midnight), Ochs stayed until daylight, spending the extra time learning the typesetting and printing trades. The present First Presbyterian Church, constructed in 1903, is a
Neoclassical building, with a Tiffany-style stained glass window. ==Layout and marker styles==