The clinical appearance is considerably varied in both the orientation, number, depth and length of the fissure pattern. There are usually multiple grooves/furrows 2–6 mm in depth present. Sometimes there is a large central furrow, with smaller fissures branching perpendicularly. Other patterns may show a mostly dorsolateral position of the fissures (i.e. sideways running grooves on the tongue's upper surface). Some patients may experience burning or soreness.
Associated conditions Fissured tongue is seen in
Melkersson–Rosenthal syndrome (along with
facial nerve paralysis and
granulomatous cheilitis). It is also seen in most patients with
Down syndrome, in association with
geographic tongue, in patients with oral manifestations of
psoriasis, and in healthy individuals. Fissured tongue is also sometimes a feature of
Cowden's syndrome. ==Cause==