The expedition sailed from
Cádiz in 1777 and arrived at
Lima in April 1778. For over ten years, from 1778 to 1788, they explored the territories of present Peru and Chile studying and collecting specimens. The expedition suffered all kinds of setbacks during this time, ranging from the sinking of the ship
San Pedro de Alcantara in 1784 that carried numerous botanical samples, a 1785 fire in the Peruvian population in Macora that resulted in the loss of additional samples and equipment, to quarrels between the members of the expeditionary team, specially between Ruiz and Dombey, that resulted in the latter leaving the group in 1784. He was replaced by Juan José Tafalla Navascués that same year. In 1788, the bulk of the expedition returned to Spain, leaving only Tafalla in Peru with a mandate to continue sending material. Painters Xavier Cortes and Jose Gabriel Rivera joined botanist Agustin Jose Manzanilla in 1793. Between 1799 and 1808, an herbarium was set up in the territory of present Quito (Ecuador) to further study the Huayaquilensis Flora, that continued making regular mailings of material to Spain until the death of Tafalla in 1811. All together, more than 3,000 specimens of plants were collected and 2,500 life-sized botanical illustrations were produced, and when they returned to Spain they brought back a great many living plants, among which was a medicinal remedy for the flu as well as toothaches, using as a base the boiled sprouts of
Buddleja incana. The collections that arrived in Cádiz in 1788 were in the most part in good condition, and were housed in Madrid's
Royal Botanical Garden and the
Gabinete de Historia Natural, the precursor of the
Museum of Natural History. The discoveries included about 150 new genera and 500 new species, which still retain the names given them by Ruiz and Pavón. Unfortunately, a part of the collection consisting of 53 crates with 800 illustrations, dried plants, seeds, resins and minerals was lost when the ship transporting it was wrecked on the coast of Portugal. ==Publications==