Radzilani was an ANC councillor in the
Makhado Local Municipality in Limpopo from 2000 to 2006, when she was appointed to a management position in the Office of the
Limpopo Premier. to 2012. The following year, she was elected to the
Provincial Executive Committee (PEC) of the ANC in Limpopo, serving as Deputy
Provincial Secretary. Radzilani was sworn in as a
Member of the
Limpopo Provincial Legislature and as
Member of the Executive Council (MEC) for Safety, Security and Liaison in the Limpopo provincial government. However, when
Stan Mathabatha took office as Limpopo Premier in July 2013, he
reshuffled his executive, firing Radzilani and replacing her with
Joyce Mashamba. Radzilani completed her term as ANC Deputy Provincial Secretary in 2014, when she was elected to a four-year term as an ordinary ANC PEC member.
VBS scandal Also in 2018, Radzilani was implicated in a major
corruption scandal at
VBS Mutual Bank when she was named in the report of an investigation commissioned by the
South African Reserve Bank. The investigation was conducted by
advocate Terry Motau, who said that Radzilani had been at the centre of "one of the most illuminating examples of the rampant corruption and
bribery that occurred" at VBS, which was declared
insolvent in 2018 after bank executives
defrauded depositors. The report reproduced
WhatsApp messages in which the former VBS chairperson, Tshifhiwa Matodzi, was informed that Radzilani had been "crying" because she had only received
R300,000 in kickbacks. Radzilani denied wrongdoing and said that Motau's report was
defamatory. Later the same week, the ANC PEC asked her and other implicated mayors to resign their government positions; Radzilani submitted her resignation letter on 11 December 2018.
Return to Limpopo Provincial Legislature: 2019–present In the
2019 general election, Radzilani was re-elected to the Limpopo Provincial Legislature. She was therefore reinstated as ANC Deputy Provincial Chairperson, and in June 2022 she won election to a second four-year term in that position. After her re-election to her ANC office, Stan Mathabatha, as Limpopo Premier, appointed her his MEC for Transport and Community Safety on 6 October 2022. She was sworn in on 11 October. Following the
2024 general election, the newly elected Premier
Phophi Ramathuba appointed her as MEC for Social Development. == Personal life ==