Its southern terminus is with
SR 16 and
County Road 13 (CR 13) near
Green Cove Springs. CR 13 continues south to
Hastings and then southeast, along old
Dixie Highway to
U.S. Route 1 (US 1, unsigned
SR 5) near
Bunnell. SR 13 is known as San Jose Boulevard for much of its run through
Duval County (coextensive with the city limits of Jacksonville). As it approaches
Downtown Jacksonville, it becomes Hendricks Avenue, then turns west along Prudential Drive and then turns into San Marco Boulevard before crossing the St. Johns River at the
Acosta Bridge. The road ends at an interchange with Riverside Avenue (former
US 17). A portion of the route that runs along the east bank of the
St. Johns River, south of Jacksonville, is designated the
William Bartram Scenic and Historic Highway. ==Major intersections==