Fossiomanus belongs to
Tritylodontidae, a clade of
cynodonts that were the last surviving lineage of non-mammalian synapsids. Tritylodontids were widely distributed during the Early Jurassic, but had become restricted to Asia by the Late Jurassic.
Fossiomanus is probably the geologically youngest known tritylodontid; its holotype specimen was found just below a
tuff layer that has been determined to be 118.9±0.8 million years old. It appears to be slightly more recent than
Montirictus, another late-surviving tritylodontid, which was found in strata constrained to be between 121.2±1.1 and 130.7±0.8 million years old. Another late-surviving tritylodontid is
Xenocretosuchus, found in the
Ilek Formation of Siberia, the age of which is poorly constrained but estimated to be
Barremian–
Aptian. Earlier tritylodontids, such as
Kayentatherium, did not have the elongate body plan that characterized
Fossiomanus. The evolution of an elongate body in
Fossiomanus may have been the result of a change in the
GDF11 or
OCT4 genes, which regulate the development of the transition from the trunk to the tail. With a total of 38 presacral vertebrae,
Fossiomanus may have been at the upper limit of the number of presacral vertebrae possible in mammaliamorphs; no known terrestrial mammal exceeds this number, although
hyraxes equal it. == References ==