Fox Odoi-Oywelowo started out as Personal Assistant to Justice J.P. Berko (Ghanaian Expatriate Judge) on an overseas Development Agency/ Judiciary Assistance Programme before serving as a legal assistant in a private law firm in
Kampala. He joined the State House Legal Department in 1995 and became the head of the department in 1996. Between 1996 and 1998, Fox Odoi-Oywelowo was part of the investigation Team into Effective Strength of the
Uganda Peoples’ Defence Forces (UPDF). The team probed the presence of ‘ghost’ soldiers on the pay rolls of the UPDF. In 1999, he led a State House special audit team into the Uganda Revenue Authority (URA), to probe tax evasion. The audit led to the introduction of systems aimed at the prevention of dumping transit goods. The audit also introduced better transit goods convoy management and re-export verification and documentation. Fox Odoi-Oywelowo is also a consummate constitutional law practitioner and has filed several constitutional petitions that have improved on the jurisprudence of Uganda. A
Locus Classicus of Fox Odoi-Oywelowo and James Akampumuza V Attorney General is taught in all law schools in Uganda. From 2000 to 2010, Odoi-Oywelowo was the head of prosecutions for Uganda People's Defence Forces unit, the Presidential Protection Unit (PPU) that later transformed into the Presidential Guard Brigade (PGB) which is currently Special Forces Command (SFC). While at State House, he was also appointed a member of the Expanded Committee of Inquiry into the causes of the clashes between the Uganda Peoples’ Defense Forces (UPDF) and the Rwanda Patriotic Front (RPF) in
Kisangani. In 2010, Odoi-Oywelowo joined the Directorate of Civil Litigation in Uganda's Justice and Constitutional Affairs Ministry, serving as senior principal state attorney. He continues to practice law as an advocate of the Courts of Judicature having enrolled in 1998. == Legislative career ==