Pickens was born in Togadoo, St Paul's Parish, in
Colleton County, South Carolina. His exact birth date varies depending on the source. Some give April 7, 1805; others give April 7, 1807. Pickens's gravestone uses the 1807 date. He was the son of former
Gov. Andrew Pickens and a grandson of
Gen. Andrew Pickens, an
American Revolutionary soldier at the
Battle of Cowpens and former
U.S. Congressman. His mother was Susannah Smith Wilkinson. A cousin of his grandmother was South Carolina
Senator John C. Calhoun. He was also a cousin of
Floride Calhoun, Calhoun's wife and a niece of his grandfather. His son-in-law was
Confederate General and U.S. Senator
Matthew C. Butler, a son of congressman
William Butler (1790-1850); grandson of congressman
William Butler and a nephew of Senator
Andrew Butler. Pickens was wealthy. According to the 1860 census, he owned $45,400 in real estate (the equivalent of approximately $1,247,000 today) and $244,206 in personal property (about $6,768,000 today). He also owned 276
slaves. Pickens was educated at Franklin College (now a part of the
University of Georgia) in
Athens, Georgia, and at
South Carolina College in
Columbia. Pickens served in Congress as a representative from South Carolina from 1834 until 1843. He was a member of the South Carolina state senate from 1844 until 1846. He was offered the position of
Minister to England by
President James K. Polk, and the Minister to France by President
John Tyler, but declined these diplomatic posts. He served as a delegate to the
Nashville Convention in 1850. Twice a widower, he married
Lucy Petway Holcombe (1832–1899) on April 26, 1856, and in 1859 she gave birth to
Douschka Pickens. Under President
James Buchanan, Pickens was Minister to Russia from 1858 to 1860, where he and his wife were befriended by
Czar Alexander II. ==American Civil War==