Liu has served as Professor, President Emeritus, and Honorary Fellow at
The Jackson Laboratory, where he was previously President and CEO from 2011 to 2021. From 2001 to 2011, he was Executive Director of the
Genome Institute of Singapore, and concurrently served as Chairman of the Governing Board of the
Health Sciences Authority of Singapore (2007–2011). Prior to that, Liu was Director of the Division of Clinical Sciences at the
National Cancer Institute (1996–2001). At the
University of North Carolina at Chapel Hill, he held several academic and leadership roles, including Chief of the Division of Medical Genetics and Professor in the Departments of Medicine, Epidemiology, Biochemistry, and Biophysics (1995–1996), Associate Professor (1993–1995), and Assistant Professor in Medicine and Oncology (1987–1993). He also directed the NIH-designated Specialized Program of Research Excellence in Breast Cancer from 1992 to 1996. ==Research==