Skaryna arrived in
Prague by 1517. According to one hypothesis, he had been a student at
Charles University in Prague, but there is no documentary evidence of this. In the same year, he rented a
printing house from a merchant named Severin in Prague and started publishing a new translation of the Bible with his own prefaces. On 6 August 1517, his first edition, , was released. "The Psalter" comprises nearly all of the biblical books of
Holy Scripture. He released new books periodically over the next few months (10 September, 6 October, 5 December, 2 January 1518, 9 January, and 19 January). Then, on 10 August 1518, he published four books at the same time. The culmination of his life's work was printing a translation of the
Bible in twenty-three books from 1517 to 1519. In 1522, Skaryna opened the first printing house in Vilnius. He published "", followed by "Apostol" in 1525. "Apostol" was released in the same order as it is used in
Orthodox worship now. Skaryna married Margarita, the widow of a Vilnius city councilor. In 1529, following his brother's death, he went to
Poznań and obtained a share of Ivan's property. In 1530, he moved with his wife to
Königsberg, but they soon returned to Vilnius. In 1532, he worked as a doctor and secretary to
John, Bishop of Vilnius. After two years, creditors of his late brother Ivan considered Skaryna as the brother's primary heir, and imprisoned him in
Poznań. He was there for several months. Roman Skaryna, Ivan's son and Francysk's nephew, actively helped his uncle, meeting with
King Sigismund I. When Skaryna was released, he sent a complaint letter with a counterclaim against the creditors to the King. In response to the letter, he was awarded two royal privilege certificates (dated 21 and 25 November 1532). These certificates exempted him from the jurisdiction of all authorities except the King. The last information about Skaryna is mentioned in the archives of 1534. He moved from Vilnius to Prague. He probably served in the royal garden in Prague until his death. The property included manuscripts, letters, and books. == Religion ==