The region may have been a major
refugium for Paleolithic peoples during the
Last Glacial Maximum, apparently playing a major role as source for the repopulation of Europe after that extremely cold period ended. From an archaeological viewpoint, Jean-Pierre Bocquet-Appel has argued that
"there are grounds for considering that the Aquitaine and French-Cantabrian refuge zone, may have been the principal source of Late Glacial re-colonization". His demographic simulations, based in archaeological data, suggest that it was the most densely populated region of Europe through all the
Upper Paleolithic. Kieran O'Hara has suggested in his book Cave Art and Climate Change that climate controlled the Franco-Cantabrian cave depictions. ==Dissolution of the regional homogeneity in the Neolithic==