Nicknamed "The Wise Guy", Buglioni made his professional debut in November 2011, stopping Sabie Montieth in the first round. He won his first 10 fights before stopping
Stepan Horvath in the eighth round in November 2013 to win the
WBO European super middleweight title. The fight went the full 12 rounds with Chudinov winning comfortably on points. In 2016, Buglioni moved up to
light heavyweight, stopping journeyman Olegs Fedotovs in the first round in March. On 10 December 2016, on the undercard of
Anthony Joshua vs. Éric Molina, Buglioni fought Hosea Burton in a tightly contested 12 round affair. With Buglioni down on the scorecards going into the 12th he produced a stunning knockout to get the win catapulting himself forwards in the rankings. It was one of the fights of 2016. Buglioni was trained by Mark Tibbs at the TRAD TKO Boxing Gym in
Canning Town, before moving on to work with the Irish boxing brothers Paschal Collins and former world champion
Steve Collins at the Celtic Warrior Boxing Gym in
Dublin, Ireland. In 2016, he moved on to new trainer Don Charles. In his first defence of the British light heavyweight title, Buglioni faced Ricky Summers. Summers held his own, but in the end Buglioni was too much for Summers and won the contest on points. In his next fight, Buglioni was slated to battle undefeated
Callum Johnson. Johnson, however, dropped shortly before the fight. He was replaced by another undefeated Brit, Craig Richards. Buglioni managed to secure the win via unanimous decision. On 24 March 2018, Buglioni and Callum Johnson finally squared of in the ring, in a bid for both the British and the Commonwealth light heavyweight titles. Johnson knocked Buglioni down and managed to finish him via TKO in the first round. On 24 November 2018, Frank fought Fanlong Meng from China, who was undefeated and was ranked #11 by the IBF. In the early rounds, Buglioni was struggling to connect on the savvy defensive Meng. As the action went on, Buglioni suffered a cut above his right eye and the doctor called for a break to take a look at the cut. The fight was initially resumed, however, the cut grew only worse, and the doctor was forced to stop the fight with 1:58 to go in the fifth round. Two days after the fight, Buglioni announced that at the age of 29, he is officially retiring from boxing. "After thoughtful deliberation; I have decided to hang up the gloves. I am proud of all my achievements in boxing and I will be forever grateful of the life lessons and positive effects it has given me." - said Buglioni as a part of his official statement. == Personal life ==