Over the course of a long life, Zindler engaged in a great number of radio, TV, and platform debates in defense of the "Wall of Separation" between state and church; the civil rights of atheists, humanists, secularists, and secularism generally; abortion rights and the right of women to control their own bodies; and the right to "death with dignity" at the end of life. He vigorously defended the teaching of evolution in public schools and the rights of LGBTQ Americans. Among his most memorable debates were his radio debate (WMUZ Detroit, Al Kresta Show, November 14, 1989) with John P. Koster (author of
The Atheist Syndrome) on the question "Does God Exist?"; his TV debate (Channel 13, Indianapolis, IN, The Dick Wolfsie Show) with John D. Morris on "The Question of Noah’s Flood"; and several radio debates (e.g., WTVN 610 AM, "Night Talk with Jim Bleikamp" in Columbus, OH) with Duane T. Gish on the question "Is Creationism Science?" He also had a famous debate with philosopher and theologian
William Lane Craig at Willow Creek Community Church, South Barrington, IL on June 27, 1993. Zindler is also a proponent of the
mythicist theory that no historical person lies behind the Gospel picture of
Jesus of Nazareth. After the publication of
Bart Ehrman's 2012 book
Did Jesus Exist? The Historical Argument for Jesus of Nazareth arguing (from a non-religious perspective) for the existence of a historical Jesus, Zindler and
Robert M. Price co-edited an anthology of essays by various mythicists arguing against Ehrman's position. ==Selected bibliography==