After Seitz published a paper on the darkening of crystals,
DuPont asked him in 1939 for help with a problem they were having with the stability of
chrome yellow. He became "deeply involved" in their research efforts. Among other things, he investigated the possible use of non-toxic
silicon carbide as a white pigment. Seitz was a director of
Texas Instruments (1971–1982) and of
Akzona Corporation (1973–1982). until 1988. Seitz later wrote that "The money was all spent on basic science, medical science," and pointed to Reynolds-funded research on
mad cow disease and
tuberculosis. "played a key role... in helping the tobacco industry produce uncertainty concerning the health impacts of smoking." According to a tobacco industry memo from 1989, Seitz was described by an employee of
Philip Morris International as "quite elderly and not sufficiently rational to offer advice." In 1984 Seitz was the founding chairman of the
George C. Marshall Institute, and was its chairman until 2001. The Institute was founded to argue for President Reagan's
Strategic Defense Initiative, but "in the 1990s it branched out to become one of the leading
think tanks trying to debunk the science of climate change." A 1990 report co-authored with Institute co-founders
Robert Jastrow and
William Nierenberg "centrally informed the
Bush administration's position on human-induced climate change". The Institute also promoted
environmental skepticism more generally. In 1994, the Institute published a paper by Seitz titled
Global warming and ozone hole controversies: A challenge to scientific judgment. Seitz questioned the view that
CFCs "are the greatest threat to the
ozone layer". In the same paper, commenting on the dangers of secondary inhalation of tobacco smoke, he concluded "
there is no good scientific evidence that passive inhalation is truly dangerous under normal circumstances." Seitz was a central figure amongst
global warming deniers. He was the highest-ranking scientist among a band of doubters who, beginning in the early 1990s, resolutely disputed suggestions that global warming was serious threat. In 2001 Seitz and Jastrow questioned whether
global warming is
anthropogenic. Seitz signed the 1995
Leipzig Declaration and, in an open letter inviting scientists to sign the
Oregon Institute of Science and Medicine's
global warming petition, called for the United States to reject the
Kyoto Protocol. even including a date of publication ("October 26") and volume number ("Vol. 13: 149–164 1999"), but was not actually a publication of the National Academy of Science (NAS). In response the
United States National Academy of Sciences took what the
New York Times called "the extraordinary step of refuting the position of one [of] its former presidents."{{Cite journal Seitz worked extensively with
Fred Singer during his consultancy career for tobacco and oil corporations in matters of health and climate change, respectively. ==Publishing==