MarketFriability
Company Profile

Friability

In materials science, friability, the condition of being friable, describes the tendency of a solid substance to break into smaller pieces under stress or contact, especially by rubbing. The opposite of friable is indurate.

General
A friable substance is any substance that can be reduced to fibers or finer particles by the action of a small amount of pressure or friction, such as rubbing or inadvertently brushing up against the substance. The term could also apply to any material that exhibits these properties, such as: • Ionically bound substances that are less than 1 kg/L in densityClay tablets • CrackersMineral fibersPolyurethane (foam) • Aerogel ==Geological==
Geological
Friable and indurated are terms used commonly in soft-rock geology, especially with sandstones, mudstones, and shales to describe how well the component rock fragments are held together. Examples: • Clumps of dried clayChalkPerlite ==Medical==
Medical
The term friable is also used to describe tumors in medicine. This is an important determination because tumors that are easily torn apart have a higher risk of malignancy and metastasis. Examples: • Some forms of cancer, such as atrial myxomaAn inflamed gallbladder ==Pharmaceutical==
Pharmaceutical
Friability testing is a laboratory technique used by the pharmaceutical industry to test the durability of tablets during transit. This testing involves repeatedly dropping a sample of tablets over a fixed time, using a rotating wheel with a baffle. The result is inspected for broken tablets, and the percentage of tablet mass lost through chipping. A typical specification will allow a non-zero percentage of chipping, and zero broken tablets. ==See also==
tickerdossier.comtickerdossier.substack.com