The college was established in 1974, by the
Marist Brothers, as Galen College, a senior campus (Yrs 11 and 12) for both male and female students. Most of its students came from the long-established St Joseph's Girls College, Ryley St, Wangaratta and Champagnat Boys College, (same venue as Galen College) an agricultural boarding school; these two schools amalgamated and formed the current Galen College in 1980 approximately. Champagnat College was established in 1955 by the
Marist Brothers on the current site in Phillipson St and was a boys only boarding school from Year Seven to Year Twelve students. By 1983, Galen was operating as a full Year 7–12, co-educational college. ==Sport==