Brown began organizing exhibitions in the early 1990s – including one for
303 Gallery in 1991 as well as pop-ups in at the
Hotel Chelsea, in his apartment on the Upper West Side and in a cubicle he rented in a Midtown office building In 2003, Brown served on the selection committee for the first edition of
Frieze Art Fair. In the early 2000s, Brown ran a gallery in
Rome called
Roma Roma Roma with fellow dealers Franco Noero and
Toby Webster, who have galleries in Turin, Italy, and Glasgow, Scotland, respectively. In 2012 he took a lease in
Los Angeles for
356 Mission, a gallery that is operated as an
artist-run space by painter
Laura Owens. In 2015, Brown and
Rirkrit Tiravanija opened Unclebrother, a restaurant and gallery in a former car dealership in
Hancock, New York. In July 2020, Brown announced that he would close his gallery and partner with Barbara Gladstone. In 2024, he donated a range of materials related to his former gallery to
Bard College’s
Center for Curatorial Studies. == Controversy ==