•
Albert Russel Erskine (1871–1933), American businessman, president of the Studebaker Corporation •
Alexander Erskine of Gogar (died 1592), Scottish landowner given charge of the child king of Scotland, James VI, from 1572 to 1578 •
Alexander Erskine, 3rd Earl of Kellie (c. 1615–1677), Scottish soldier •
Alexander Erskine of Cambo (c. 1663–1727), Lord Lyon King of Arms •
Anne Erskine (1739–1804), Scottish aristocrat, friend and trustee of Selina, Countess of Huntingdon •
Arthur Erskine (1881–1963), British soldier and courtier •
Arthur Erskine of Blackgrange (died 1571), Scottish courtier •
Barbara Erskine (born 1944), English novelist •
Carl Erskine (1926–2024), American Major League Baseball pitcher •
Charles Erskine (disambiguation) •
Chester Erskine (1905–1986), American director, producer, and writer of Broadway plays and films •
Chris Erskine (born 1987), Scottish footballer •
Claudius James Erskine (1821–1893), British Indian civil servant, judge and vice-chancellor of the University of Calcutta •
David Erskine (disambiguation) •
Deborah Erskine (born 1990 or 1991), politician from Northern Ireland •
Ebenezer Erskine (1680–1754), Scottish minister whose actions led to the establishment of the Secession Church •
Emmanuel Erskine (1937–2021), Ghanaian army general and commander of the United Nations Interim Force in Lebanon and the United Nations Truce Supervision Organization •
Gary Erskine (born 1968), Scottish comic book artist •
George Erskine (1899–1965), British general •
George Elphinstone Erskine (1841–1912), British Indian Army major general •
Gizzi Erskine (born 1979), British chef and TV personality •
Graves B. Erskine (1897–1973), United States Marine Corps general •
Henry Erskine (disambiguation) •
Ilene Erskine (1933–2018), Scottish educational psychologist, artist and printmaker. •
Jacob Erskine (born 1989), English footballer •
James Erskine (disambiguation) • Jared Samuel Erskine (born 1986), stage name
October London, American singer and songwriter •
Joe Erskine (American boxer) (1930–2009), welterweight boxer and long-distance runner •
Joe Erskine (Welsh boxer) (1934–1990), British and British Empire heavyweight boxing champion •
John Erskine (disambiguation) •
Kathryn Erskine, American 21st century writer of children's literature •
Kenneth Erskine (born 1963), British serial killer known as the "Stockwell Strangler" •
Laurie York Erskine (1894–1976), American author and educator •
Margaret Erskine (disambiguation) •
Marilyn Erskine (born 1926), American retired actress •
Mary Erskine (1629–1707), Scottish businesswoman and philanthropist •
Maya Erskine (born 1987), American actress and writer •
Peter Erskine (born 1954), American jazz drummer and composer •
Peter Erskine (artist) (born 1941), American artist •
Peter Erskine (businessman), British businessman •
Ralph Erskine (architect) (1914–2005), British-Swedish architect •
Ralph Erskine (historian) (1930–2021), Northern Ireland government lawyer and historian of wartime codebreaking •
Ralph Erskine (minister) (1685–1752), Scottish clergyman •
Randy Erskine (born 1948), American golfer •
Robert Erskine (disambiguation) •
Roy Erskine (born 1931), Scottish footballer •
Ruaraidh Erskine (1869–1960), Scottish nationalist activist •
Scott Erskine (1962–2020), American serial killer •
Thomas Erskine (disambiguation) •
Walter Erskine, Earl of Mar and Kellie (1839–1888) •
Walter Erskine, Earl of Mar and Kellie (1865–1955) •
Wendy Erskine (born 1968), Northern Irish author and teacher •
William Erskine (disambiguation) ==Fictional characters with the surname==