Harrison married Mary Feilde, daughter of Edward Feilde of Stanstead Abbots, Hertfordshire on 12 June 1737. He died without issue on 2 December 1759, leaving his principal estate to his niece
Audrey or Etheldreda, who married
Charles Townshend, 3rd Viscount Townshend. This was with the proviso that it was to be free from any "intermeddling" from her husband, from whom she separated formally around 1740. As well as Edward, his brother
Thomas Harrison, and brother-in-law
Edward Hughes were also Members of Parliament. ==References==