He was a younger son of
James Talbot, 3rd Baron Talbot of Malahide, a British intelligence chief of the
French Revolutionary Wars period, and his wife Anne Sarah Rodbard, daughter of Samuel Rodbard of
Evercreech, Somerset. He was educated at
Eton College, where he was a pupil by 1829. Talbot matriculated at
Balliol College, Oxford in 1834. He graduated B.A. at
St Mary Hall in 1839, and took up the position of vicar of Evercreech in 1840. He graduated M.A. in 1841. He trained for the Catholic priesthood at Oscott, with
Edward Henry Howard and
Edmund Stonor, lifelong friends. He was ordained priest by Wiseman in 1846. In 1847 he was rebuffed by
John Henry Newman, when he offered to join Newman's proposed English branch of the
Congregation of Oratorians. In the period 1848–9 he worked as a priest at
St George's, Southwark. ==In Rome==