From the route's western start at
SR 40 Conn in Folkston, the route runs east, through rural areas, to its eastern end at
US 17/
SR 25/
SR 110 in White Oak. Known as MLk Dr in Folkston and Burnt Fort Road in Camden county, SR 252 runs past the D. Ray James Prison and provides the most direct route between Folkston and Brunswick, via US 17. ==History==