Pergolini made her international debut at the
2017 World Para Swimming Championships where she won a silver medal in the
100 metre backstroke S13. She again represented the United States at the
2019 World Para Swimming Championships where she won a silver medal in the
100 metre backstroke S13. During the 2018 U.S. Paralympics Swimming Para National Championships, she set the American record in the 100 metre backstroke S13 with a time of 1:07.97. Pergolini, just 17 years old, competed in the
100 metre backstroke S13 event at the
2020 Summer Paralympics where she set a world record with a time of 1:05.05 in the qualifying heats. She broke the world record again in the finals with a time of 1:04.64, winning the gold medal. On April 14, 2022, Pergolini was named to the roster to represent the United States at the
2022 World Para Swimming Championships. On June 30, 2024, Pergolini was named to team USA's roster to compete at the
2024 Summer Paralympics. At the Paralympics she won a gold medal in the
100 metre backstroke S13, and a silver medal in the
50 metre freestyle S13 events. This was Team USA's first gold medal of the games. She competed at the
2025 World Para Swimming Championships and won gold medals in the
50 metre freestyle S13 and
100 metre backstroke S13 events. ==References==