Sacchetti was presented by
Antonio Barberini, at the instruction of
Cardinal Mazarin, the French first minister, as the French nomination for the
papacy at the
papal conclave of 1644. So certain of victory was Sacchetti's brother Matteo, that he threw open the doors of his cellar and began giving away wine in celebration shouting, "Viva Papa Sacchetti!" (
Long live Pope Sacchetti!). Spain, fearing he would be pro-French,
vetoed his nomination via its representative
Cardinal Gil de Albornoz. The conclave instead elected Giovanni Battista Pamphili, who took the papal throne as
Pope Innocent X. Mazarin attempted to use the French veto against Pamphili, who apparently favoured the Spanish, but it arrived too late. Despite his close association with the Barberini, who suffered under Innocent X, Giulio Sacchetti's career continued to flourish. When Innocent X died, Sacchetti was again presented as the French candidate at the
papal conclave of 1655 but when it became apparent that he did not have a majority, he asked Mazarin to give his support to Fabio Chigi, who was duly elected and took the name of
Alexander VII. ==Death and burial==